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Methylcobalamin Vitamin B12 — Naturally Occurring
• Naturally occurring coenzyme form used by the body.
• Active “ready-to-use” form; minimal conversion required by the body.
• Often chosen by those preferring natural products.
• Works well in sublingual tablets and sprays.

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Cyanocobalamin Vitamin B12 — Synthetically Created
• Requires conversion to active forms after absorption.
• Contains a cyanide ligand; trace cyanide released during metabolism.
• Often used mainly because it’s cheaper to manufacture.
• May be less suitable for people with impaired conversion or kidney issues due to trace cyanide.

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Key considerations for Methylcobalamin VS Cyanocobalamin:

Vitamin B12 is a complex molecule centered around a cobalt ion. In cyanocobalamin, a cyano group (-CN) is attached to this cobalt ion. The name itself, "cyano-cobalamin," reflects this chemical composition. This cyanide ligand is not naturally present in the forms of B12 found in food sources but is introduced during the manufacturing process because it stabilizes the molecule, making it more shelf-stable.

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When you ingest cyanocobalamin, your body works to convert it into the two active forms of Vitamin B12 that it can actually use: methylcobalamin and adenosylcobalamin. This conversion process involves the removal of the cyanide ligand. The small amount of cyanide that is released is then typically converted in the liver to a less toxic compound called thiocyanate, which is then excreted in the urine.

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The medical community generally considers the amount of cyanide released from typical doses of Cyanocobalamin supplements to be physiologically insignificant and not harmful for the vast majority of people. They do however, recommend only Methylcobalamin Vitamin B12 for individuals with certain rare metabolic conditions or those with kidney failure, since the body's ability to clear this cyanide may be impaired. 

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By choosing the active, natural form of the vitamin (Methylcobalamin), you are providing your body with a nutrient that it can use directly without engaging the detoxification system to filter cyanide.

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Mini Barn Market sells only Vitamin B12

with 100% Methylcobalamin purity.

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“Educational content only — not medical advice. Consult a clinician for testing & treatment.”